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CD8+NKT-like cells regulate the immune response by killing antigen-bearing DCs
CD1d-dependent NKT cells have been extensively studied; however, the function of CD8(+)NKT-like cells, which are CD1d-independent T cells with NK markers, remains unknown. Here, we report that CD1d-independent CD8(+)NKT-like cells, which express both T cell markers (TCRβ and CD3) and NK cell receptors (NK1.1, CD49b and NKG2D), are activated and significantly expanded in mice immunized with GFP-...
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ژورنال
عنوان ژورنال: Journal of Experimental Medicine
سال: 2007
ISSN: 1540-9538,0022-1007
DOI: 10.1084/jem.2046iti3